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Post-marketing reports have described rare cases of intestinal obstruction in patients taking GLP-1 receptor agonists, potentially related to severely delayed gastric and intestinal transit [9]

The rapid increase in the use of these medications has led to supply challenges and resulted in the proliferation of compounded analogs, raising concerns about safety and bioequivalence [45]

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Dihexa consistently outperformed these analogs, likely due to its superior metabolic stability and enhanced c-Met binding affinity

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