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Studies with semaglutide show that discontinuation leads to appetite returning to baseline levels and weight regain of approximately two-thirds of the lost weight within one year

Last reviewed: June 2, 2026 Last updated: June 2, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

If youre ready to explore a medically supervised weight-loss approach that goes beyond typical dieting, Dr

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