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Peters says the industry is still understanding some of the potential risks of these medications, and it will be important to identify who may be at greater risk for those issues
Diabetes 64 , 25132525 (2015)
This triple agonism strategy builds upon the remarkable clinical success of dual GLP-1/GIP agonists like tirzepatide, which have shown unprecedented weight loss efficacy, by adding a third mechanism - glucagon receptor activation - to further enhance metabolic benefits, particularly energy expenditure and hepatic fat oxidation
Muscle tissue is metabolically active
10.1186/s12950-019-0218-y 18 RizzaR
Doseresponse effects on HbA 1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial
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