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Apremilast (Otezla) is an oral anti-inflammatory drug that is approved by the Food and Drug Administration (FDA) for plaque psoriasis and psoriatic arthritis (FDA 2014

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Figure 2 provides a schematic representation of how GLP-1 R activation on key retinal cells orchestrates a coordinated protective response, integrating neuroprotective, anti-inflammatory, and vasoprotective actions through convergent signaling pathways

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10.1111/j.1464-5491.2008.02484.x