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DOI: 10.1038/s41467-025-60844-9

Pregnancy and breastfeeding increase B12 requirements, and pregnant women with B12 deficiency may need more frequent monitoring and potentially adjusted treatment schedules

Briefly, the total RNA from HepG2 cells and liver tissues was isolated using TRIzol (#15596026, Invitrogen, Waltham, MA, USA)

Provider assessment should integrate these contextual factors alongside genetic predispositions to establish safe, individualized acetaminophen thresholds rather than applying population-average recommendations universally

Due to its lipophilic nature, Mel easily penetrates cell membranes and acts as a potent antioxidant by scavenging hydroxyl and peroxyl radicals.15 This antioxidant effect is mediated through increased activity of Glutathione Peroxidase (GSH-Px) and Superoxide Dismutase (SOD), prevention of Catalase Reduction (CAT), and inhibition of Nitric Oxide Synthase (NOS)

SP signal peptide