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In order to be able to fight free radicals and endure oxidative stress, spermatozoa require a strong membrane containing a sufficient amount of essential constituents - mainly Glutathione
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Andersson O, Adams BA, Yoo D, Ellis GC, Gut P, Anderson RM, et al (2012) Adenosine signaling promotes regeneration of pancreatic cells in vivo
Together, these preclinical findings strongly indicate that ferroptosis is not a secondary consequence of neurodegeneration in AD, but rather functions as an upstream pathogenic mechanism that drives A production, tau hyperphosphorylation, and neuronal apoptosis
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