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Injuries to tendons or ligaments
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The typical patient has a soft-tissue injury that stalled: they completed physical therapy, have no surgical indication, but are still symptomatic at 8 to 12 weeks
Telomere length is therefore studied as one aspect of ageing biology
The results indicate that FOXO4-DRI potently and selectively reduces the viability of senescent fibroblasts compared to non-senescent controls (2.7-fold and 1.7-fold difference for keloid and normal skin, respectively)
The peptide reaches peak plasma concentrations within 30 minutes and distributes to various tissues including liver, kidney, gastrointestinal tract, and injured tissues
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