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The limited available human clinical evidence evaluating BPC-157 and related peptide therapies in musculoskeletal settings is summarized in Table 2

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Interaction of the programmed cell death 1 molecule (PD-1) expressed by T cells with its ligands PD-L1 and PD-L2, which are expressed by isolated hBECs, was shown to be a key factor in migration (Pittet et al., 2011), whereas PECAM-1 was not crucial (Wimmer et al., 2019)