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The connection between abnormal iron metabolism in tumor stem cells and iron dependent deathhighlights the potential of iron dependent deathas a promising target in combating tumor stem cells, enhancing treatment efficacy, and reversing drug resistance (Xu et al., 2023)

Absolute contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, active pregnancy, and severe diabetic retinopathy in some cases

The weakened tissue of the mitral valve can mean that as well as parachuting upwards into the left atrium, the valve leaflets can stop closing together properly, allowing some blood to flow the wrong way, leaking from the left lower pumping chamber (the left ventricle) back into the upper chamber rather than out into the aorta to the body