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How to set meaningful VO max targets based on age, sex, long-term decline, and desired physical capabilities later in life [51:15]

Adverse events were what you would expect from an incretin-class drug in a supervised trial: nausea in 42.4 percent of 12 mg patients versus 14.8 percent on placebo, diarrhea in 32.0 percent versus 13.5 percent, vomiting in 25.3 percent versus 4.8 percent

Microdosing promotes gradual, sustainable weight loss

However, people who are particularly sensitive to changes in blood sugar, hydration, or electrolyte levels might experience symptoms like palpitations while taking any GLP-1 receptor agonist

Dose reduction of these medications may be needed to reduce hypoglycaemia risk

Missed doses during the loading phase are the usual reason a stall shows up in weeks 35