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Older adults may have higher risk factors for B12 deficiency due to gastrointestinal disorders, dietary factors, or certain medications (like proton pump inhibitors or metformin) that can interfere with B12 absorption

Whether that translates into additive weight loss in humans is the open empirical question

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Monitor Homocysteine High homocysteine levels are linked to stroke, mood disorders, PCOS, and pregnancy complications

In some cases, yes but only if the vial will be used entirely in a single session, since sterile water doesnt contain a preservative to keep it safe for repeated use