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The -subunit is structurally homologous to those of LH, FSH, and TSH

A health care professional can determine how long someone should continue taking the medication after meeting their weight loss goals

00:01:41 Steve Small: And for the purposes of disclosure, none of the speakers today have anything to disclose

In animal models, DSIP administration has been associated with reduced markers of oxidative damage and improved mitochondrial function, supporting its use in studies of neuronal resilience and metabolic stability [6]

We expect to dose the first patient and report initial data in the second half of 2026. Later this year, Fractyl expects to expand the study to additional sites in Australia, where the company has already submitted a clinical trial application and is currently awaiting a response from regulators