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SWI/SNF chromatin remodeler ARID1A-deficient cancer cells show vulnerability towards oxidative stress that arises from GSH depletion due to the reduced expression of the SLC7A11 cysteine transporter, which also regulates folate metabolism [41,189]

Management strategies: Rotate injection sites preventing localized reactions, inject after eating reducing nausea risk, start lower doses titrating up gradually, take with food and plenty of water, monitor blood pressure if known hypertension, discontinue immediately if signs of allergy (hives, difficulty breathing, facial swelling)

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However, evidence for cosmetic skin transformation is still emerging