This capability supports the development of personalized protocols, improving efficacy while minimizing side effects [231, 235, 236]
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The hydrophilicity of DFO also limits its permeability through the cells, including neurons (Kontoghiorghes and Kontoghiorghe, 2016), requiring higher doses that can increase the risk of severe systemic side effects such as cardiomyopathy, hepatic or renal failure, and neurotoxicity (Xu et al., 2024)
Most athletes can maintain their regular training schedule, though some may find they can increase training volume due to enhanced recovery
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