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Funding This work was supported by the Department of Orthopaedic Surgery, University of Pittsburgh School of Medicine (to HL) and the Albert B

* Correspondence: Xun Wu, [email protected] These authors have contributed equally to this work ORCID: Tanwei Fang, orcid.org/0009-0006-0404-7553 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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