More recently, it has become famous for its skin-lightening properties
doi: 10.1530/joe-20-0155 50 ZhangLWangFLiDYan Y and WangH
Glutathione is also the obligate substrate for glutathione S-transferases (GSTs), the enzyme family responsible for phase II hepatic detoxification conjugating GSH to electrophilic xenobiotics, heavy metals, and endogenous toxins to render them water-soluble and excretable
If administered by injection, local reactions such as redness, tenderness, itching, or swelling can occur
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Improved mood and mental clarity (11-14% of reviews) A subset of the energy-improvement group specifically mentions mood elevation, reduced anxiety, or "mental sharpness." This aligns with B12's role in neurotransmitter synthesis and methylation reactions affecting serotonin and dopamine pathways (Kennedy, Nutrients , 2016)
