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The induction of SMADs via EV39 was notable, given that human intestinal organoid cultures typically require a TGF1 receptor inhibitor (A83-01) for long-term maintenance 105

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SunXOuZChenRNiuXChenDKangRet alActivation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

These peptide signals are integrated with higher-level endocrine feedback

In the future, this technology can also be combined with gene editing or even laser editing techniques to achieve proximity labeling of target proteins and rapidly annotate the related physiological processes caused by protein interactions