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The findings indicate that microbial metabolite 4-ethylphenyl sulfate (4EPS) enters the brain and is associated with changes in region-specific activity and functional connectivity, including altered oligodendrocyte function, impaired oligodendrocyte maturation, and decreased oligodendrocyte-neuron interactions (Needham et al., 2022)

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Mannose-mediated nanodelivery of methotrexate to macrophages augments rheumatoid arthritis therapy

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Another study, which followed 933 adults for a 10-year period, reported that persons who ate larger amounts of high glycemic index carbohydrates had a 77% greater risk of cataracts compared to those who ate mostly low glycemic index carbohydrates (Tan 2007)