Since Sirtuin 3 (SIRT3), the major NAD+-dependent deacetylase, is primarily expressed in neurons [31] and is exclusively located in the mitochondria [41], it plays an important role in regulating mitochondrial function, metabolism, antioxidative defense systems, and energy metabolism [42]
This allows the molecule to travel safely through the digestive tract and be absorbed directly into the bloodstream
In fact, research shows that proper site rotation can cut irritation by up to 50%, making the process much more comfortable for you
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Abreu et al
[1] Picomolar activity is unusual for a small peptide and suggests high-affinity receptor-mediated signaling, though the specific receptor for GHK-Cu has never been identified