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(2015), BioMed Research International 2015:648108, PubMed 26236730 Statistics from research literature Discovered by Loren Pickart in human blood plasma in 1973 , as a factor extending the longevity of cultured liver cells The smallest peptide with documented pharmacological activity: 3 amino acids (Gly-His-Lys) + one Cu ion Molecular weight: 402 Da EU cosmetic INCI name: Copper Tripeptide-1 (registered in EU Commission CosIng database) Gene expression modulation: 4 000 human genes (Connectivity Map dataset, Pickart 2015) Plasma level in healthy humans declines from ~200 ng/mL at age 20 to ~80 ng/mL at age 60 (62 % decrease) Most-studied bioactivities: fibroblast proliferation , type I/III collagen synthesis , antioxidant activity (SOD upregulation) Reference sources (PubMed) Pickart L., Vasquez-Soltero JM., Margolina A
Geranylgeranylacetone ameliorates beta-amyloid toxicity and extends lifespan via the heat shock response in Caenorhabditis elegans
If you have lab work scheduled, let your care team and your provider know so the timing can be handled correctly
Its a clinical dose of creatine monohydrate (5 grams per serving) that gets the job done
[PubMed] [Google Scholar] 95.Zitzmann S, Ehemann V, Schwab M
Ongoing research in mice has focused on the potential of Receptor Grade IGF-1 LR3 in possibly mitigating the progression of a wide range of conditions such as muscle atrophy, dementia, and kidney disease
