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Efficacy and safety of liraglutide versus placebo as add-on to glucose-lowering therapy in patients with type 2 diabetes and moderate renal impairment (LIRA-RENAL): a randomized clinical trial

Hillege et al

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Rationale, design and baseline characteristics of REMODEL, a mechanism-of-action trial with semaglutide in people with type 2 diabetes and chronic kidney disease

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While both medications have shown great promise, tirzepatides dual action on both GLP-1 and GIP might give it the edge in terms of overall efficacy, particularly when it comes to weight loss