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It takes a whole lot longer to build or accrue benefit, and then half as much to erase all that benefit, said Al-Aly, who is also chief of the Research and Development Service at the VA Saint Louis Health Care System

A patient arrives having heard about Wegovy or Mounjaro perhaps from a news article, perhaps from a friend who has lost significant weight, and the discussion centres almost entirely on efficacy and tolerability

If convenience and portability matter more, capsules win

LaFrance J

Summary: This phase 2 trial, a precursor to the phase 3 studies, provided the initial evidence for the superior efficacy of the CagriSema combination

A PGC-1-dependent myokine that drives brown-fat-like development of white fat and thermogenesis