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Compared with the TG group, the ALC + TG group exhibited significantly decreased protein and mRNA SREBP2 and HMGCR levels (Figures 6AC)

Therefore, HTY may represent one of the components of olive oil contributing to chemopreventive effects in the colon, including reported inhibitory effects in cultured human colon adenocarcinoma cells [84]

L-carnitine could increase mitochondrial function [6]

Orlistat, one of its components, acts by inhibiting fat absorption in the gastrointestinal tract, while Levocarnitine contributes to fat metabolism, promoting its utilization as an energy source

Diabetes is a chronic condition, and GLP-1 therapy is usually intended for long-term management

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