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Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance

A salty taste can occur when saliva levels change or the mouth becomes dry

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This leads to increased intracellular calcium, which activates calcium/calmodulin-dependent protein kinase kinase (CaMKK), subsequently stimulating AMP-activated protein kinase (AMPK)

Als Nebenwirkungen knnen zum Beispiel Magen-Darm-Beschwerden, wie etwa Durchfall, auftreten