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Interestingly, Rae-1 expression was induced on endothelial cells from primary melanoma (B16) and correlated with reduced NK cell anti-tumor functions (116)

(/ GSH) : / : Liposomal Glutathione : S-Acetyl L-Glutathione (SAG) : : N-Acetyl Cysteine (NAC) + Glycine GSH & L-Glutathione Reduced : L-Glutathione Reduced , GSH

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Recombinant human insulin-like growth factor-1 (IGF-1) and Dulbeccos Modified Eagle Medium/Nutrient Mixture F-12 (DMEM-F12), Tryp-LE, Horse Serum, and phosphate-buffered saline (PBS) were purchased from Life Technologies (Thermo Fisher Scientific, Waltham, MA, USA)

the former cooperates with copper in synthesizing cytoplasmic SOD1, while the latter constitutes mitochondrial SOD2