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GLP-1 receptor agonist injections, such as Mounjaro and Wegovy, are supported by robust clinical evidence, demonstrating 15-25% weight loss in trials

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Regular walking or other light physical activity may also support healthy digestion

Retatrutide can plausibly cause heartburn-type symptoms because its GLP-1 receptor activity slows gastric emptying, increasing intra-gastric pressure and the likelihood of acid reflux

Aydin , et al