In one trial, artichoke extract (1,800 mg/day) for six weeks reduced total cholesterol (-9.9%) and LDL cholesterol (-16.6%) in 71 hypercholesterolemic patients, with no differences in HDL cholesterol or triglycerides
glutathione plays a key role in most of these antioxidant mechanisms
Illustratively, in the mentioned laser-wound studies, human albumin solder supplemented with transforming growth factor (TGF)-1 only, but not with HB-EGF or bFGF, increased the early postoperative strength of laser-welded wounds (Poppas et al., 1996), even though the superpulsed CO 2 laser enhanced fibroblast replication and appeared to stimulate bFGF and inhibit TGF-1 secretion (Saghazadeh et al., 2018
However, low polyphenol content olive oil did not further modify HDL levels, while high polyphenol olive oil increased HDL-cholesterol concentration by almost 50% (Tsartsou, Proutsos, Castanas, & Kampa, 2019)
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