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& Remage-Healey, L
The ligament is forced to resist not only the forward translation of the tibia but also the inward collapse and rotation of the knee joint
Evidence points to the 2-hydroxyestrone metabolite as perhaps the safest estrogen metabolite, so it earns the label of good estrogen, although it is not without potential problems
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However, it remains unapproved by the FDA and banned for human use in many countries due to the lack of human trials and concerns over safety, contamination, and legal misuse
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