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doi: 10.1002/humu.23315 40

doi: 10.1172/jci.insight.133429 26 Barreto-ViannaARCAguilaMBMandarim-de-LacerdaCA

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On the other hand, estrogens phenolic hydroxyl group can act as an anti-oxidant agent, being a protective factor against cardiovascular and neurodegenerative diseases (Kumar et al., 2010)

Glutathione can trigger detoxification symptoms such as headaches, nausea, and fatigue

For researchers using IGF-1 LR3 as a tool to study these pathways, the practical advantage is that sustained receptor activation enables longer time-course studies of pathway dynamics