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Mechanistically, multi-omics analyses of cardiac and hepatic tissues revealed that semaglutide exerted these benefits by improving cardiac metabolism, interfering with pro-fibrotic and pro-hypertrophic signals, and by reducing systemic inflammation

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Additionally, correlations between OS biomarkers and parasite load have been observed [142], as well as improvements in antioxidant defense following successful therapy, indicating that OS may be a useful tool for monitoring the treatment and clinical follow-up of sick dogs [140]