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Unfortunately many studies that have looked at antioxidants and treatments that potentially support the redox pathway did not use biomarkers to measure redox metabolism status in the participants or the effect of treatment on redox pathways

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& Klagsbrun, M

Small-molecule fluorescent/chemiluminescent probes Small-molecule fluorescent/chemiluminescent probes are powerful but require disciplined controls: H 2 O 2 reporters (Amplex-type, HRP-coupled) are highly sensitive for extracellular or compartment-averaged H 2 O 2 yet pool signals from multiple sources and can be confounded by endogenous peroxidases and scavengers, so include catalase or catalase-mimetics as negative controls and state explicitly whether readouts reflect intra- versus extracellular H 2 O 2 (Zhou et al

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On the other hand, the treatment group showed resistance to muscle loss and maintained muscle strength