semaglutide does it work How to Know If Is Working: Signs and Timeline How Long Does it Take

3 years on from their introduction, one of the most fascinating elements of the GLP-1 drug rollout, is the variation in responses from one person to another, something I looked at in this recent piece for the Irish Examiner

These observations reinforce the need for well-designed randomised controlled trials (RCTs) to validate the findings and expand the evidence base

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Thats great for weight lossbut if overnight youre going from eating 3,000 calories per day to 1,500 calories, thats a sudden drop in your energy supply, and your body will need some time to adjust

They're close to the results seen in the STEP 1 trial, where participants lost 15% of their starting weight on average with injectable semaglutide

You may need to draw slightly more to reach your target after expelling the air