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The study's authors said they did not conduct any statistical analysis across all of the studies because of differences between study designs

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As retatrutide is an investigational medicine, any adverse events must be reported through your trial's reporting pathway in line with the study protocol

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As with all GLP-1 agonists, long-term post-marketing surveillance will be essential to characterize the pancreatic safety profile with greater statistical precision, particularly for rare events such as acute pancreatitis (estimated background rate of approximately 35 per 100,000 person-years in the general population) and the theoretical concern about pancreatic cancer