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Retatrutide : This triple agonist (GLP-1 + GIP + glucagon) produced 28.7% weight loss in Phase 3 but introduced a new safety signal: dysesthesia (abnormal skin sensations) in 4.4 to 20.9% of participants at the 12 mg dose depending on trial population

FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice

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