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These new findings encourage a novel working hypothesis for further research, that a chemical-modification mechanism enables transformation of HGF through interaction or reaction with LASSS under physiological conditions, resulting in the retention of HGFs biological activity after exposure to peroxynitrite, at least until an enhanced form of HGF undergoes metabolic turnover in vivo
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Toxicity of Biologically Active Peptides and Future Safety Aspects: An Update
As seen in AgRP GHR KO mice, both LepR GHR KO and brain GHR KO mice showed defects in their ability to save energy during F.R
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