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At supraoptimal concentrations, PROTAC molecules increasingly form non-productive binary complexes (PROTAC-POI or PROTAC-E3) rather than the desired ternary complex [102, 103]
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It can be argued that they are particularly stable due to exchange energy, though Cann suggests it is not the most adequate explanation and instead forwards the "parallel spin avoidance factor"
Antioxidants 12 (1), 45
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All the assessments were carried out by trained postgraduates team in health sciences (from three different disciplines: nutrition, physiotherapy, and biomedical sciences) who were completely blinded about the intervention groups
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