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2.4 Ligaments, meniscus, and peri-articular muscles In OA, ligaments, especially the cruciate (ACL/PCL) and collateral ligaments, undergo both structural and biochemical deterioration

Diabetes with cardiovascular disease Cardiovascular disease (CVD) is a prevalent comorbidity in patients with diabetes, where T2DM patients are subject to a two- to three-fold increase in the risk of developing CVD, with a reported co-prevalence exceeding 30% [67, 68]

To discard a putative strain dependence of this phenotype, we constructed the ahpD in a D39 genetic background, the ancestral strain for R6 and R801 strains, and we found the same H 2 O 2 susceptibility observed in the R801 strain (Fig S3), and this will be discussed later

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S2CID 57512164