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More appropriate tumor characterization and prognosis have become possible with refinements in newer multiplex panel IHC over the last few years

In mesothelioma models, SFN disrupts PRMT5/MEP50 complex function, inhibiting its methyltransferase activity, reactivating tumor suppressor expression, and suppressing cancer cell proliferation, invasion, and stem-like properties (79, 80)

Liver histopathology was examined by a blinded pathologist

Employing gene editing techniques alongside both in vivo and in vitro experiments, we provide novel evidence that the dysfunction of SLC25A39-mediated mitochondrial import of GSH constitutes a pathological alteration following TBI, leading to mitochondrial dysfunction and subsequent initiation of oxidative stress and neuronal cell death

Aug 2015;30(8):1325-1331

Assessment of the clinical use of IV and oral NAC in the treatment of acute acetaminophen poisoning in children: a retrospective review