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For example, one study used an ASO to target a hairpin structure in the 5 UTR region of the LDLR mRNA that was inhibitory to protein translation, which resulted in an increase of LDLR protein expression and LDL uptake in HEK293T cells [82]

These models help researchers explore how cells maintain functional stability during environmental or biological stress

These changes can appear within days, especially after the first few injections

Dark spot on labia (or lip)

Retinoblastoma - Strabismus (crossed eyes), a whitish or yellowish glow through the pupil, decreasing/loss of vision, sometimes the eye may be red and painful

However, it is not yet widely used in the field of pharmacovigilance