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(2) AOD 9604s designation as a modified version of fragment 176-191 positions it to potentially induce lipolysis, possibly without significant impacts on insulin and IGF-1 levels, mitigating potential risks associated with glucose intolerance and diabetes

10.1038/s41392-022-00889-0 131 LinW.WangC.LiuG.BiC.WangX.ZhouQ.et al (2020)

In order to ascertain the optimal time point, lapatinib at the concentration of 10 M was treated in the different time points: pretreatment for 6 h (pre 6 h), pretreatment for 2 h (pre 2 h), co-treatment with Glu or erastin (pre 0 h) and posttreatment for 2 h (post 2 h)

In the D-Gal + FOXO4-DRI group, mice also received D-galactose injections and, after 4 weeks, were given intraperitoneal injections of FOXO4-DRI (5 mg/kg, MCE, HY-P4157) every 2 days for 4 weeks, followed by tissue collection