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0.7% and 3.8%, 6.3%, 8.0% vs

The Phase 2 result of 24.2% at 48 weeks came from a general obesity population without an OA requirement and is more broadly applicable as a benchmark

Journal of Affective Disorders , 322, 1-9

The 2.5 mg starting dose is explicitly a tolerability dose in trials it was not intended to drive weight loss on its own, but to let the gut acclimate before therapeutic doses begin

Lower doses target general health and anti-aging benefits while higher doses are needed for significant body composition effects

Stronger is not always the same as better for you. Which medication causes the most weight loss