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Frequently Asked Questions about B12 Shots for Hangovers Do B12 injections help with hangovers

Additionally, a randomized, double-blind, placebo-controlled trial in 2,588 healthy older adults with mild hyperhomocysteinemia found that daily supplementation with 500 g of vitamin B 12 and 400 g of folic acid for two years reduced blood homocysteine concentrations but had no benefit on depressive symptoms in those with or without depressive symptoms at baseline (110)

This common belief usually stems from an incorrect inference that B12 supplements have an appetite-stimulating effect

Quality Control in Research Compounds: COA and HPLC Testing for Metabolic Studies. Analytical Chemistry Reviews , 54(1), 78-95

This will increase your personal comfort, but will also allow you to eat food to restore your electrolytes

Maintain sterile handling practices