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This means: Lyophilized (freeze-dried) powder is far more stable than reconstituted solution because water activity drives hydrolysis and oxidation

V., Yen, L

miR-26a-5p, hsa-miR-181c-3p, hsa-miR-126-5p, hsa-miR-22-3p, hsa-miR-148b-5p, hsa-miR-106b-3p, hsa-miR-6119-5p, hsa-miR-1246, and hsa-miR-660-5p was recently reported to differentiate between AD and healthy controls with an AUC ROC reaching 85%, in a study that comprised one of the biggest cohorts of AD patients (Guo et al., 2017)

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Peptides were eluted into the Orbitrap Exploris 480 at a flow rate of 200 nl min 1

Shaking is catastrophic for peptide integrity