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The SWI/SNF (BAF) complex, an ATP-dependent chromatin remodeling complex in the nucleus that endows DNA with the capacity for replication and enables selective gene expression and DNA repair and recombination, is frequently mutated in human cancers and thus exerts a great impact on tumorigenesis 51

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NDI1 is a rotenone (Rot)-insensitive, non-proton-translocating NADH dehydrogenase that regenerates NAD + and transfers electrons to ubiquinone 26 (Fig

The primary risks involve the quality of the drug substances used