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or signs of allergic reaction such as rash, itching, swelling, or difficulty breathing

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These are fundamentally different physiologic targets, making direct substitution inappropriate without clinical reassessment

The proportion of obese patients (BMI 30 kg/m 2 ) fell from 71.0% to 43.3% in the semaglutide group versus 71.9% to 67.9% in the placebo group

La Vignera S, Condorelli RA, Vicari E, DAgata R, Calogero AE

In fact, this is the most clinically dangerous numeric entry error there is