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The key findings were: Tirzepatide met the primary goal of cardiovascular non-inferiority , confirming it is at least as safe for the heart as dulaglutide It did not quite meet statistical superiority over dulaglutide for MACE, although results trended in favour of tirzepatide Tirzepatide produced significantly greater reductions in HbA1c and body weight than dulaglutide Importantly, because SURPASS-CVOT used an active comparator with established cardiovascular benefit rather than a placebo, demonstrating superiority was inherently more difficult than in earlier placebo-controlled GLP-1 outcome trials

(2015) 166:6205.e624

If youve starting to see and feel the effects of aging, whether its brain fog, fatigue, weight gain, or just not bouncing back like you used to, what if we told you the most powerful strategy for looking and feeling younger (especially after 40) isnt your lifestyle habits, medical aesthetics, or plastic surgery