However, if you have hit a plateau on tirzepatide, if you have stubborn visceral fat that is not responding, or if you want to maximize the fat-to-lean-mass loss ratio, the addition of AOD 9604 provides a mechanistically sound enhancement
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doi: 10.1016/j.phrs.2023.106668 16 DuYDaiJMaoLWeiXBaiXChenLet al
This is confirmed by an increase in the production of proinflammatory cytokines IL-1, IL-6 and TNF-, through migration of the transcription factor NF-, the activating protein (AP-1) and cyclooxygenase 2 (COX2) activation [123]