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When enough anomalies accumulate, they create what Kuhn calls a crisis, a loss of confidence in the status quo because the existing paradigms no longer apply

Br J Ophthalmol 1995;79:54-56

The potential role of gut microbiome composition is a theoretical consideration that has not yet been substantiated by robust clinical evidence in this context

"One theory behind this side effect is that Ozempic can affect the levels of certain hormones in the body, including glucagon-like peptide-1 (GLP-1)," Purdy explained

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The sarco/endoplasmic reticulum calcium ATPase pump transports intracellular calcium into the sarcoplasmic or endoplasmic reticulum of the cardiac, skeletal, and vascular smooth muscle cells