Monitor your progress closely and adjust your approach as needed to achieve optimal results
Notably, many of these compounds show effects even at low or nanomolar concentrations, which are often more pronounced in obesity conditions
In a statement, Novo Nordisk said researchers clearly disclose their relationships with the company and that it works with external researchers and experts to ensure the studies are conducted with the highest standards and ultimately meet patient needs.

Patients considering creatine after gastric sleeve surgery are strongly encouraged to: Consult their bariatric dietitian before starting any new supplement Ensure protein targets are being met before adding performance-focused supplements Have renal function and routine bloods checked as part of postoperative monitoring, and inform their clinician they are taking creatine Be aware of the transient water-weight gain associated with creatine and discuss this with their team Choose reputable, third-party tested products (e.g., Informed Sport certified) to reduce contamination risk Report any new or concerning symptoms such as oedema, changes in urine output, or persistent GI disturbance to their GP promptly In summary, while creatine may offer some benefits for muscle preservation and physical performance in post-bariatric patients, the evidence base in this specific population remains limited
A representative patient (Pem020) is shown in Supplementary Table S1 and Supplementary Fig
They are considered for: Patients with type 2 diabetes: Individuals whose blood sugar remains high despite using first-line diabetic medications like metformin may benefit from adding a GLP-1 agonist