The sarcopenia problem in older GLP-1 patients does not disappear, so Regeneron still has a use case but itll be outside neurodegenerative conditions
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The key to targeting these stubborn areas is CLA
Muscle-preserving nutrition strategiesadequate protein, resistance exercise, and hydrationbecome critical on GLP-1 therapy to ensure weight loss is primarily from fat mass rather than lean tissue loss
For example, Kyle , age 11, demonstrated marked improvement in object tracking and coordination, enhancing both his reading and physical abilities
The GLP-1 receptor is expressed primarily in pancreatic beta cells, the gastrointestinal tract, and certain areas of the central nervous system, with limited expression in skeletal muscle tissue